JUVÉDERM® VOLUMA™ XC injectable gel is a smooth, colorless hyaluronic acid (HA) gel that contains a small quantity of local anesthetic (lidocaine). HA is a naturally occurring sugar found in the human body that deliver nutrients and help the skin retain improves the comfort of the injection. JUVÉDERM® VOLUMA™ XC injectable gel is manufactured using VYCROSS® technology; during which, a small amount of the biodegradable compound BDDE is added to crosslink the HA in the gel. VYCROSS® technology results in a specialized smooth-gel filler that produces long-lasting results at the treatment site. JUVÉDERM® VOLUMA™ XC is delivered by an injection into the cheek and surrounding area of the mid-face to correct volume and fullness.
JUVÉDERM® VOLUMA™ XC is indicated for deep (subcutaneous and / or supraperiosteal) injection for cheek augmentation to correct age related volume deficit in the mid-face in adults over the age of 21.
As you age, the cheek area loses its youthful shape. The cheeks flatten out and the skin may begin to sag. JUVÉDERM® VOLUMA™ XC injectable gel is designed to temporarily reverse these signs of aging. It is a gel that is injected into the cheek area to lift the skin. It temporarily adds volume to the cheek area and results in a smoother contour and more youthful appearance to the face.
It is injected into the cheek area using a small needle or cannula. It temporarily corrects volume in the cheek area and gives the appearance of a more youthful, smoother skin surface.
It will temporarily correct volume in the cheeks and cheek area that has been lost due to aging and will provide a smoother contour and more youthful appearance to the face.
Injections may cause some discomfort during and after the procedure. In the JUVÉDERM® VOLUMA™ XC injectable gel clinical study, immediately after injection subjects rated injection pain, on average, as a 3 on an 11-point scale where 0 is no pain and 10 is worst pain imaginable. JUVÉDERM® VOLUMA™ XC injectable gel contains lidocaine to reduce injection site pain. Your doctor may also choose to numb (anesthetize) the treatment area with a topical or injected numbing agent to further minimize discomfort.
In the clinical trial the most common side effects were temporary reactions at the treatment site such as tenderness, swelling, firmness, and lumps/bumps. These side effects generally lasted 2 to 4 weeks. See Section 14 for additional information on side effects seen in the clinical study. Your doctor will also tell you what to expect following treatment with JUVÉDERM® VOLUMA™ XC injectable gel. Within the first 24 hours, you should minimize strenuous exercise and exposure to extensive sun or heat. Exposure to any of the above may increase temporary redness, swelling, and/or itching at the injection site. If there is swelling, you may place an ice pack over the swollen area. You should ask your doctor when makeup may be applied after your treatment.
You should discuss your treatment goals and plan with your doctor. In the clinical study, 82% of subjects received a touch-up treatment 1 month after initial treatment in order to achieve the desired result.
No. While individual results may vary, in the clinical study, the results lasted up to 2 years in a majority of subjects treated with JUVÉDERM® VOLUMA™ XC. After this, repeat injections are usually needed to maintain your desired result.